Premier League Predictions GW4: Manchester United Face Derby Defeat as Liverpool Aim to Stay Perfect

Story: written by Okafor joseph September 13,2025
The Premier League returns this weekend with blockbuster fixtures, including the highly anticipated Manchester derby at the Etihad Stadium and Liverpool’s bid to continue their flawless start to the season.
Manchester City vs Manchester United
All eyes will be on Sunday’s clash as Pep Guardiola’s Manchester City host rivals Manchester United. City head into the derby as favourites, boasting an unbeaten start and firing on all cylinders. United, meanwhile, remain inconsistent, and another derby defeat could pile pressure on manager Erik ten Hag.
Liverpool vs Burnley
At Anfield, Arne Slot’s Liverpool are tipped to maintain their perfect record when they face Burnley. The Reds have looked sharp in attack and solid at the back, with new signings settling quickly into the squad. Anything less than three points would be a shock.
Other Key Fixtures
- Arsenal vs Aston Villa: The Gunners face a tricky test against a confident Villa side, but Mikel Arteta’s men are expected to edge the encounter.
- Chelsea vs Brighton: Chelsea will look to bounce back from a mixed start, though Brighton’s high-pressing style could make life difficult at Stamford Bridge.
- Tottenham vs Newcastle: Spurs, under Ange Postecoglou, continue to entertain with their attacking football, but Newcastle’s physicality could pose problems.
As the race for the Premier League title begins to take shape, this weekend’s matches could prove pivotal in setting the tone for the weeks ahead.